Liver transplantation is a surgical procedures carried out to replace the failing liver with donor liver. Liver, a vital organ of human body has several essential functions to perform.
1. Filters and disposes the toxic materials from the blood
2. Fuels the human body with the energy needed for the body to function
3. Generates the Blood Clotting factors
4. Prevents virus and various other infections
5. Regulates the cholesterol levels, sex hormones, vitamins and minerals in the body.
All the above said functions are affected because of liver cirrhosis or liver failure. When the liver is extremely damaged the only solution for survival and successful treatment is liver transplantation.
Medanta Institute of Liver Transplantation and Regenerative Medicine in Gurgaon is one of the most modern and the largest tertiary hospital in India established by Dr.A.S.Soin who is a expertise Liver transplant Surgeon in India. As a leading Liver Transplant Consultant in India he dedicated his Medanta- The Medicity Hospital for Liver Treatment facility with 150 beds and carrying out nearly 250 liver transplants and hundreds of biliary tract and complex liver surgeries every year.
Chronic liver failure can happen over the years or it can happen suddenly within few weeks called as acute liver failure. The scar in the liver due to cirrhosis prevents the function of liver and transplant has to be done. This may appear due to hepatitis virus or due to long term alcohol abuse. Other reasons for liver transplant are
Liver disease due to alcohol
Biliary duct atresia
Chronic hepatitis B & C
Liver cancer (early stage)
Fatty liver disease
Hemochromatosis (excess iron)
Primary sclerosis cholangitis (the bile ducts get inflammation, scarring and destroyed)
Primary biliary cirrhosis ( scarring in the liver due to inflammation of bile ducts blocking the flow of bile)
Wilson’s disease (excess copper in the body may be a inherited condition)
Next to heart disease, chest infections, stroke and cancer liver disease is the most common cause of death. Liver transplantation is carried out by replacing the patient’s liver with the new liver taken from a brain dead, heart beating donor (Deceased Donor Liver Transplant, DDLT) or a living donor (Living Donor Transplant, LDLT). In DDLT the complete liver is taken for transplant while from living donor only half of the liver is taken for transplantation. Liver, a unique organ of the human body has a special capacity of regeneration which greatly facilitates for liver transplantation from living donor. The remaining liver in the donor and also in the recipient grows well and achieves the full functional level within 3 to 4 weeks.
Any person above the age of eighteen can donate liver and in India as per Human Organ Act 1996 liver donation can be done only to family members like son, daughter, father, mother, brother, sister or to any close relatives. Regarding medical fitness of liver donor, he or she should be of compatible blood group i.e., O group or the same group of the recipient. And the donor should not be above the age of 55, psychologically sound and medically fit. The voluntary live donors are thoroughly evaluated for surgical and medical fitness.